SCHEMBL7260723

SCHEMBL7260723

C1=CCC(COCOCC2CC=CCC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.49
CDK1 P06493 2/20 0.41
CCNB1 P14635 2/20 0.41
CCNA2 P20248 2/20 0.41
CDK2 P24941 2/20 0.41
CCNA1 P78396 2/20 0.41
ALDH1A1 P00352 5/20 0.38
LMNA P02545 4/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 2/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
KDM4E B2RXH2 5/20 0.34
APOBEC3A P31941 2/20 0.34
APOBEC3G Q9HC16 2/20 0.34
RGS12 O14924 2/20 0.34
PABPC1 P11940 1/20 0.34
EIF4H Q15056 1/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973683 0.91 MAPK1 (0.56) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL12286212 0.83 MAPK1 (0.46) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL14241127 0.83 MAPK1 (0.46) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL16480957 0.83 MAPK1 (0.46) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL472171 0.83 MAPK1 (0.46) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL13895288 0.79 MAPK1 (0.44) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL7927729 0.78 ALDH1A1 (0.44) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL19695510 0.78 ALDH1A1 (0.44) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL13460203 0.78 MAPK1 (0.57) MAPK1CDK1CCNB1CCNA2CDK2
SCHEMBL13188777 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777671-B Continuous process for epoxidizing olefins using supported heteropolyacids 长春人造树脂厂股份有限公司 2021-01-15 CN disclosed
US-20170357156-A1 NEGATIVE TONE PHOTOSENSITIVE COMPOSITIONS PROMERUS, LLC (US) 2017-12-14 US disclosed
US-9499505-B2 Process for the epoxidation of olefins CHANG CHUN PLASTICS CO., LTD. (TW) 2016-11-22 US disclosed
US-9499505-B2 Process for the epoxidation of olefins CHANG CHUN PLASTICS CO., LTD. (TW) 2016-11-22 US disclosed
US-9499505-B2 Process for the epoxidation of olefins CHANG CHUN PLASTICS CO., LTD. (TW) 2016-11-22 US disclosed
US-20160177023-A1 CONTINUOUS PROCESS OF OLEFINIC EPOXIDATION BY SUPPORTED HETEROPOLY ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2016-06-23 US disclosed
US-20160177023-A1 CONTINUOUS PROCESS OF OLEFINIC EPOXIDATION BY SUPPORTED HETEROPOLY ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2016-06-23 US disclosed
US-20160177023-A1 CONTINUOUS PROCESS OF OLEFINIC EPOXIDATION BY SUPPORTED HETEROPOLY ACID CHANG CHUN PLASTICS CO., LTD. (TW) 2016-06-23 US disclosed
US-20160083360-A1 PROCESS FOR THE EPOXIDATION OF OLEFINS CHANG CHUN PLASTICS CO., LTD. (TW) 2016-03-24 US disclosed
US-20160083360-A1 PROCESS FOR THE EPOXIDATION OF OLEFINS CHANG CHUN PLASTICS CO., LTD. (TW) 2016-03-24 US disclosed
US-20160083360-A1 PROCESS FOR THE EPOXIDATION OF OLEFINS CHANG CHUN PLASTICS CO., LTD. (TW) 2016-03-24 US disclosed
WO-2003057677-A1 ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES SYDDANSK UNIVERSITET (DK) 2003-07-17 WO disclosed
EP-0532896-B1 Cleavable diepoxide for removable device protection in electronic packaging IBM (US) 1997-03-19 EP disclosed
US-5560934-A CURED REACTION PRODUCT CONTAINING A CYCLIC ANHYDRIDE CURING AGENT AND AN AMINE PROMOTER; USED FOR ENCAPSULATING ELECTRONIC CHIPS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-10-01 US disclosed
US-5512613-A CURED COMPOSITION COMPRISING REACTION PRODUCT OF DIEPOXIDE HAVING ACETAL LINKAGES, CYCLIC DICARBOXYLIC ANHYDRIDE CURING AGENT, 1,3-DIAZA COMPOUND, HYDROXY FUNCTIONAL INITIATOR; REMOVABLE IN ACIDIC SOLVENTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-04-30 US disclosed
EP-0532896-A2 Cleavable diepoxide for removable device protection in electronic packaging International Business Machines Corporation (US) 1993-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083360-A1 PROCESS FOR THE EPOXIDATION OF OLEFINS HSF1, HMOX1, HSPH1 MAPK1 1550/4885CDK1 2739/4885CCNB1 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.