Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13896218 | 0.85 | HTR6 (0.48) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL9662668 | 0.76 | HTR6 (0.51) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL731798 | 0.75 | HTR6 (0.61) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL2319101 | 0.75 | HTR6 (0.57) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL3243357 | 0.75 | HTR6 (0.50) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL29207366 | 0.74 | HTR6 (0.55) | HTR6CA1CA2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL27814998 | 0.74 | HTR6 (0.59) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL2026702 | 0.72 | HTR6 (0.57) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL16242806 | 0.72 | HTR6 (0.57) | HTR6CA1CA2MAOAMAOB | |
| SCHEMBL4714587 | 0.71 | HTR6 (0.51) | HTR6CA1CA2PIN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745015-B1 | BICYCLIC AROMATIC SULFINYL DERIVATIVES | CEPHALON INC (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8314155-B2 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC (US) | 2012-11-20 | — | — | US | disclosed |
| US-8314155-B2 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC (US) | 2012-11-20 | — | — | US | disclosed |
| US-20090042907-A1 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042907-A1 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-7423176-B2 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423176-B2 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC. (US) | 2008-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042907-A1 | Bicyclic aromatic sulfinyl derivatives | SULT2A1, TPST2, AHR | HTR6 216/4885CA1 4740/4885CA2 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.