Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581791 | 0.92 | EPHX1 (0.51) | MAPTLMNAALDH1A1EPHX1HTT | |
| SCHEMBL19091261 | 0.86 | ALDH1A1 (0.56) | MAPTLMNAALDH1A1EPHX1HTT | |
| SCHEMBL21357360 | 0.85 | EPHX1 (0.48) | MAPTLMNAALDH1A1EPHX1HTT | |
| SCHEMBL6280635 | 0.85 | EPHX1 (0.62) | MAPTLMNAALDH1A1EPHX1HTT | |
| SCHEMBL22579080 | 0.84 | NAMPT (0.50) | LMNAALDH1A1EPHX1HTTKMT2A | |
| SCHEMBL22579084 | 0.84 | NAMPT (0.50) | LMNAALDH1A1EPHX1HTTKMT2A | |
| SCHEMBL17030473 | 0.84 | KEAP1 (0.52) | MAPTALDH1A1EPHX1HTTKMT2A | |
| SCHEMBL28420696 | 0.81 | EPHX1 (0.65) | LMNAALDH1A1EPHX1HTTKMT2A | |
| SCHEMBL3851790 | 0.81 | EPHX1 (0.51) | MAPTLMNAALDH1A1EPHX1HTT | |
| SCHEMBL6275597 | 0.81 | HTT (0.58) | MAPTLMNAALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8313885-B2 | Lithographic printing plate precursor comprising bi-functional compounds | AGFA GRAPHICS NV (BE) | 2012-11-20 | — | — | US | disclosed |
| US-20070105041-A1 | Lithographic printing plate comprising bi-functional compounds | AGFA-GEVAERT (BE) | 2007-05-10 | — | — | US | disclosed |