Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MYOC | Q99972 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581791 | 0.88 | EPHX1 (0.51) | HTTKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL19091261 | 0.83 | ALDH1A1 (0.56) | HTTKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22609165 | 0.83 | ALDH1A1 (0.57) | HTTKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL29606242 | 0.83 | MAPT (0.52) | POLBKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1558275 | 0.82 | MAPT (0.58) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL21357360 | 0.82 | EPHX1 (0.48) | HTTKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6280635 | 0.82 | EPHX1 (0.62) | HTTKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22579080 | 0.81 | NAMPT (0.50) | HTTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22579084 | 0.81 | NAMPT (0.50) | HTTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13896286 | 0.81 | MAPT (0.46) | HTTKMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105257-A1 | CHROMATOGRAPHIC STATIONARY PHASE FOR SEPARATION OF CYCLODEXTRINE AND DERIVATIVES THEREOF | CHIROQUEST KIRÁLIS TECHNOLÓGIÁKAT FEJLESZTÖ KFT. (HU) | 2005-11-10 | — | — | WO | disclosed |