Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | PPM1B | O75688 | 2/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13897096 | 1.00 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL9058122 | 1.00 | CHRM1 (0.44) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL9057991 | 0.94 | PPM1B (0.49) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL15985614 | 0.80 | PPM1B (0.51) | PPM1BNPSR1ALDH1A1PTPN1PPP1CC | |
| SCHEMBL13897030 | 0.79 | TSHR (0.38) | PPM1BALDH1A1PTPN1PPP1CC | |
| SCHEMBL15981931 | 0.76 | PPARG (0.49) | PPM1BCA12CA1CA2CA9 | |
| SCHEMBL25397026 | 0.76 | PPM1B (0.59) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL13906553 | 0.76 | PPM1B (0.59) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL2140593 | 0.76 | ALDH1A1 (0.46) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL1627201 | 0.76 | PPM1B (0.49) | PPM1BSMN1; SMN2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072650-A1 | Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods | UNIVERSITY OF MASSACHUETTS (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072650-A1 | Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods | UNIVERSITY OF MASSACHUETTS (US) | 2013-03-21 | — | — | US | disclosed |
| US-8329927-B2 | Water-soluble and water-insoluble, ring opening metathesis polymerization products, monomers and related methods | UNIVERSITY OF MASSACHUSETTS (US) | 2012-12-11 | — | — | US | disclosed |
| US-8329927-B2 | Water-soluble and water-insoluble, ring opening metathesis polymerization products, monomers and related methods | UNIVERSITY OF MASSACHUSETTS (US) | 2012-12-11 | — | — | US | disclosed |
| WO-2009039407-A1 | WATER-SOLUBLE AND WATER-INSOLUBLE, RING OPENING METATHESIS POLYMERIZATION PRODUCTS, MONOMERS AND RELATED METHODS | UNIVERSITY OF MASSACHUSETTS (US) | 2009-03-26 | — | — | WO | disclosed |
| US-20090082524-A1 | Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods | UNIVERSITY OF MASSACHUSETTS (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090082524-A1 | Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods | UNIVERSITY OF MASSACHUSETTS (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082524-A1 | Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods | CD14, MAGI3, NOD2 | CHRM1 3720/4885CHRM2 4580/4885CHRM4 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.