Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14386236 | 0.80 | MAPT (0.56) | PEPDMAPTGAAALDH1A1THRB | |
| SCHEMBL12824893 | 0.78 | KIF11 (0.55) | MAPTKDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL5761295 | 0.77 | ALDH1A1 (0.58) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL1322717 | 0.75 | PEPD (1.00) | PEPDMAPTGAAALDH1A1THRB | |
| SCHEMBL12209638 | 0.75 | MAPT (0.60) | PEPDMAPTGAAALDH1A1THRB | |
| SCHEMBL1822006 | 0.75 | ALDH1A1 (0.65) | PEPDMAPTGAAALDH1A1THRB | |
| SCHEMBL447770 | 0.75 | PEPD (0.60) | PEPDMAPTGAAALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL1593109 | 0.73 | PEPD (0.58) | PEPDMAPTGAAALDH1A1THRB | |
| SCHEMBL5580193 | 0.71 | PEPD (0.56) | PEPDMAPTGAAALDH1A1THRB | |
| SCHEMBL9812574 | 0.71 | GAA (0.61) | PEPDMAPTGAAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034308-A2 | PROCESS FOR THE PREPARATION OF A RAF KINASE INHIBITOR AND INTERMEDIATES FOR USE IN THE PROCESS | CIPLA LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |