Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | GAA | P10253 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TYR | P14679 | 1/20 | 0.62 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PEPD | P12955 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725810 | 0.89 | ALDH1A1 (0.75) | ALDH1A1GAAMAPTKDM4ETHRB | |
| SCHEMBL8705118 | 0.80 | GAA (0.65) | ALDH1A1GAAMAPTKDM4ETHRB | |
| SCHEMBL728343 | 0.80 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTL3MBTL1TSHR | |
| SCHEMBL12071790 | 0.80 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTKDM4ETHRB | |
| SCHEMBL28916359 | 0.78 | CA2 (0.60) | ALDH1A1GAAMAPTKDM4ETHRB | |
| SCHEMBL11751583 | 0.78 | ALDH1A1 (0.61) | ALDH1A1GAAMAPTL3MBTL1TSHR | |
| SCHEMBL449122 | 0.78 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTKDM4ETHRB | |
| SCHEMBL526059 | 0.78 | MAPT (0.63) | ALDH1A1GAAMAPTKDM4ETSHR | |
| SCHEMBL652231 | 0.78 | IDO1 (0.63) | ALDH1A1GAAMAPTTSHRTP53 | |
| SCHEMBL5518697 | 0.78 | IDO1 (0.63) | ALDH1A1GAAMAPTTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730947-B | 2,4, 5-Trisubstituted thiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2024-07-02 | — | — | CN | claimed |
| CN-115449136-B | Accelerator composition of rubber nanocomposite as well as preparation method and application thereof | 浙江大学 | 2024-02-27 | — | — | CN | claimed |
| CN-116730947-A | 2,4, 5-trisubstituted thiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2023-09-12 | — | — | CN | claimed |
| CN-115449136-A | Accelerator composition of rubber nanocomposite and preparation method and application thereof | 浙江大学 | 2022-12-09 | — | — | CN | claimed |
| CN-114307994-A | Preparation method and application of hydrogel adsorbent for Au (III) recovery | 郑州大学 | 2022-04-12 | — | — | CN | claimed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | claimed |
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-116730947-B | 2,4, 5-Trisubstituted thiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2024-07-02 | — | — | CN | disclosed |
| CN-116730947-B | 2,4, 5-Trisubstituted thiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2024-07-02 | — | — | CN | disclosed |
| CN-115449136-B | Accelerator composition of rubber nanocomposite as well as preparation method and application thereof | 浙江大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-116730947-A | 2,4, 5-trisubstituted thiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2023-09-12 | — | — | CN | disclosed |
| CN-116730947-A | 2,4, 5-trisubstituted thiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2023-09-12 | — | — | CN | disclosed |
| US-20230279426-A1 | MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION | LYCIA THERAPEUTICS, INC. | 2023-09-07 | — | — | US | disclosed |
| WO-1992008721-A1 | NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | LUCKY, LTD. (KR) | 1992-05-29 | — | — | WO | disclosed |
| EP-0397511-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY, LTD. (KR) | 1990-11-14 | — | — | EP | disclosed |
| US-4816235-A | Silver and manganese recovery using acidified thiourea | PESIC BATRIC (US) | 1989-03-28 | — | — | US | disclosed |
| US-4778519-A | Recovery of precious metals from a thiourea leach | PESIC BATRIC (US) | 1988-10-18 | — | — | US | disclosed |
| US-4514346-A | Method of making thermal-shock resistant molded articles on the basis of silicon carbide | KERNFORSCHUNGSANLAGE JULICH GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-30 | — | — | US | disclosed |
| US-4293592-A | Method for production of printed circuits by electroless metal plating | HITACHI, LTD. (JP) | 1981-10-06 | — | — | US | disclosed |
| US-3994719-A | Resins for separating heavy metals consisting of thiourea-group-containing macroporous vinyl aromatic crosslinked matrixes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279426-A1 | MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION | HAVCR2, ASGR1, FCGR3B | ALDH1A1 4368/4885GAA 1239/4885MAPT 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.