Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31017545 | 0.77 | PRKCI (0.38) | TAAR1PRKCIACHETSHRGAA | |
| SCHEMBL25280713 | 0.77 | PRKCI (0.38) | TAAR1PRKCIACHETSHRGAA | |
| SCHEMBL217189 | 0.77 | PRKCI (0.42) | TAAR1PRKCIACHETSHRGAA | |
| SCHEMBL22722975 | 0.76 | TSHR (0.43) | PRKCIACHETSHRGAAMAPT | |
| SCHEMBL28578528 | 0.76 | CASP1 (0.37) | PRKCIACHETSHRGAAMAPT | |
| SCHEMBL12844067 | 0.74 | TAAR1 (0.38) | TAAR1PRKCIACHETSHRGAA | |
| SCHEMBL31303603 | 0.73 | PRKCI (0.62) | TAAR1PRKCIACHETSHRGAA | |
| SCHEMBL2665541 | 0.73 | CYP3A4 (0.52) | TAAR1PRKCITSHRGAAMAPT | |
| SCHEMBL30574669 | 0.73 | TAAR1 (0.38) | TAAR1ACHEMAPTMAPK1HTT | |
| SCHEMBL10034977 | 0.73 | ALDH1A1 (0.52) | TAAR1PRKCIACHETSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034308-A2 | PROCESS FOR THE PREPARATION OF A RAF KINASE INHIBITOR AND INTERMEDIATES FOR USE IN THE PROCESS | CIPLA LIMITED (IN) | 2009-03-19 | — | — | WO | disclosed |