Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 12/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | DRD4 | P21917 | 6/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892595 | 1.00 | CCR5 (0.60) | CCR5DRD2DRD4SLC18A3 | |
| SCHEMBL3891405 | 0.82 | CCR5 (0.48) | CCR5DRD2DRD4SLC18A3 | |
| SCHEMBL13898261 | 0.82 | CCR5 (0.48) | CCR5DRD2DRD4SLC18A3 | |
| SCHEMBL8211043 | 0.82 | SLC6A2 (0.57) | CCR5DRD2DRD4SLC18A3 | |
| SCHEMBL8030434 | 0.78 | SLC18A3 (0.67) | CCR5DRD2SLC18A3 | |
| SCHEMBL445421 | 0.77 | DRD2 (0.69) | DRD2DRD4 | |
| SCHEMBL5363060 | 0.77 | DRD2 (0.60) | DRD2DRD4 | |
| SCHEMBL6160819 | 0.76 | DRD2 (0.55) | CCR5DRD2DRD4 | |
| SCHEMBL3890369 | 0.76 | DRD2 (0.52) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7227645 | 0.76 | CCR5 (0.55) | CCR5DRD2DRD4SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |