Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.58 |
| ▸ | MMP13 | P45452 | 15/20 | 0.46 |
| ▸ | MMP14 | P50281 | 10/20 | 0.45 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP3 | P08254 | 8/20 | 0.45 |
| ▸ | MMP9 | P14780 | 8/20 | 0.45 |
| ▸ | MMP8 | P22894 | 8/20 | 0.45 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | MMP10 | P09238 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983663 | 0.93 | MMP1 (0.58) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL13898999 | 0.89 | MMP1 (0.46) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL3987272 | 0.85 | MMP1 (0.68) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL6870820 | 0.84 | MMP1 (0.58) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL3921083 | 0.84 | MMP1 (0.55) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL6873149 | 0.84 | MMP1 (0.70) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL6813262 | 0.84 | MMP1 (0.67) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL6813516 | 0.84 | MMP1 (0.54) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL3923765 | 0.83 | MMP1 (0.66) | MMP1MMP13MMP14MMP2MMP3 | |
| SCHEMBL6809651 | 0.83 | MMP1 (0.68) | MMP1MMP13MMP14MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |