Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898938 | 0.88 | MMP1 (0.57) | MCL1MMP1MMP2MMP9 | |
| SCHEMBL3921084 | 0.81 | RORC (0.45) | MCL1MMP1BCL2L1HTTSMN1; SMN2 | |
| SCHEMBL3922883 | 0.79 | MMP1 (0.56) | MCL1MMP1MMP2MMP9 | |
| SCHEMBL3914343 | 0.78 | MMP1 (0.60) | MCL1MMP1MMP2MMP9 | |
| SCHEMBL13898999 | 0.74 | MMP1 (0.46) | MMP1MMP2MMP9NR3C1PTGES | |
| SCHEMBL6809653 | 0.73 | MMP1 (0.62) | MMP1NR3C1SMN1; SMN2 | |
| SCHEMBL8502159 | 0.73 | MMP1 (0.69) | MMP1MMP2MMP9PTGESALOX5 | |
| SCHEMBL5852079 | 0.73 | PLAU (0.49) | HTTSMN1; SMN2 | |
| SCHEMBL13902863 | 0.72 | MMP1 (0.45) | MMP1MMP2MMP9NR3C1PTGES | |
| SCHEMBL6689128 | 0.71 | MMP1 (0.65) | MMP1MMP2MMP9NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |