Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | MMP14 | P50281 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898985 | 0.75 | NR3C1 (0.43) | MMP1SMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL27500507 | 0.73 | MMP1 (0.54) | MMP1SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL13898992 | 0.72 | MCL1 (0.50) | MMP1SMN1; SMN2HTTNR3C1MMP2 | |
| SCHEMBL8502159 | 0.72 | MMP1 (0.69) | MMP1SMN1; SMN2LMNAHTTMMP2 | |
| SCHEMBL6809653 | 0.70 | MMP1 (0.62) | MMP1SMN1; SMN2PLGPLAUPLAT | |
| SCHEMBL6689128 | 0.68 | MMP1 (0.65) | MMP1SMN1; SMN2PLGPLAUPLAT | |
| SCHEMBL3914710 | 0.66 | MMP1 (0.78) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL3913080 | 0.65 | MMP1 (0.59) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL6876444 | 0.65 | MMP1 (0.81) | MMP1LMNAMMP2MMP9MMP8 | |
| SCHEMBL8443684 | 0.65 | MMP1 (0.51) | MMP1ALDH1A1POLBNR3C1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |