SCHEMBL13899482

SCHEMBL13899482

C=C(OC12CC3CC(C1)CC(C(=O)NS(C)(=O)=O)(C3)C2)C(C)(C)CC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.36
HSD11B2 P80365 1/20 0.36
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.33
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
SCN9A Q15858 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2734992 0.89 HSD11B1 (0.37) HSD11B1HSD11B2PKMLMNATHRB
SCHEMBL13899589 0.78 ALDH1A1 (0.47) LMNA
SCHEMBL10188085 0.77 PKM (0.34) PKMLMNATHRBDPP8DPP9
SCHEMBL13899608 0.74 DPP8 (0.38) DPP8DPP9
SCHEMBL12603699 0.74 PKM (0.38) HSD11B1PKMDPP8DPP9
SCHEMBL10225229 0.72 ALDH1A1 (0.31)
SCHEMBL2734993 0.71 ALDH1A1 (0.47) LMNA
SCHEMBL2618626 0.70
SCHEMBL12932666 0.70 NPSR1 (0.37) PKMLMNADPP8DPP9
SCHEMBL14802401 0.70 DPP8 (0.39) DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504194-B2 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION (JP) 2009-03-17 US disclosed
US-20070134590-A1 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION. (JP) 2007-06-14 US disclosed