Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 12/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972843 | 0.87 | FFAR1 (0.39) | ITGB1ITGA4 | |
| SCHEMBL13899767 | 0.86 | KLKB1 (0.45) | ITGB1ITGA4ITGB3ITGAVITGA5 | |
| SCHEMBL3978072 | 0.85 | GPR34 (0.45) | ITGB1ITGA4ITGB7ITGB2ICAM1 | |
| SCHEMBL3976460 | 0.84 | UTS2R (0.39) | FNTAFNTB | |
| SCHEMBL3979310 | 0.80 | TACR3 (0.44) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL3979314 | 0.80 | TACR3 (0.44) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL3969892 | 0.79 | RAB9A (0.51) | — | |
| SCHEMBL3969899 | 0.79 | RAB9A (0.51) | — | |
| SCHEMBL5926900 | 0.78 | ITGB1 (0.47) | ITGB1ITGA4ITGB7ITGB2ICAM1 | |
| SCHEMBL5926295 | 0.78 | ITGA4 (0.44) | ITGB1ITGA4ITGB7ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501538-B2 | Aryl and heteroaryl compounds, compositions and methods of use | TRANSTECH PHARMA, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501538-B2 | Aryl and heteroaryl compounds, compositions and methods of use | TRANSTECH PHARMA, INC. (US) | 2009-03-10 | — | — | US | disclosed |