Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.31 |
| ▸ | CTSA | P10619 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389768 | 0.90 | GPBAR1 (0.33) | PPARGPPARABRD4 | |
| SCHEMBL1389771 | 0.90 | GPBAR1 (0.33) | PPARGPPARABRD4 | |
| SCHEMBL369104 | 0.88 | PPARG (0.38) | PPARGPPARAPOLB | |
| SCHEMBL1390289 | 0.87 | CXCR3 (0.37) | BRD4CXCR3CTSA | |
| SCHEMBL369210 | 0.85 | CXCR3 (0.39) | POLBCXCR3 | |
| SCHEMBL371110 | 0.85 | POLB (0.36) | BRD4POLBKEAP1NFE2L2L3MBTL1 | |
| SCHEMBL370348 | 0.83 | MRGPRX4 (0.42) | PPARGBRD4 | |
| SCHEMBL368732 | 0.83 | MAPT (0.42) | BRD4CXCR3 | |
| SCHEMBL371041 | 0.83 | FFAR1 (0.37) | BRD4POLBCXCR3 | |
| SCHEMBL370157 | 0.82 | GPBAR1 (0.39) | BRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |
| US-8765730-B2 | 1-hydroxyimino-3-phenyl-propanes | Hoffmann-La Roche Inc (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120010190-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010190-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | GPBAR1, GPR119, ADRB1 | PPARG 161/4885PPARA 235/4885BRD4 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.