Tetrahydrofuran

Tetrahydrofuran

SCHEMBL139042

C1CCOC1.CCOCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.33
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL3966212 1.00 ALDH1A1 (0.50) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL2114570 1.00 ALDH1A1 (0.50) ALDH1A1TSHRHTTLMNAPOLB
Dioxane SCHEMBL8034299 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL28163248 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL10676279 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Ether SCHEMBL463356 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL28266595 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Ether SCHEMBL1559716 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Ether SCHEMBL4417828 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL8982353 0.97 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2737 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344796-A Corrosion-resistant wear-resistant impact-resistant anti-adhesion polyurea material for inner wall of railway wagon and preparation method thereof 山西华豹新材料有限公司 2024-07-16 CN claimed
CN-114989387-B Bi-component polyurethane-polyurea elastomer and preparation method and application thereof 无锡博锦高分子研究发展有限公司 2024-07-05 CN claimed
US-20240209149-A1 BIO-BASED POLYAMIDE ELASTOMER AND PREPARATION METHOD THEREFOR CATHAY BIOTECH INC. (CN) 2024-06-27 US claimed
CN-118240190-A Low-temperature-resistant polycaprolactone polyol, preparation method of low-temperature-resistant polycaprolactone polyol and polyurethane resin thereof, and ink 湖南聚仁新材料股份公司 2024-06-25 CN claimed
CN-118222021-A Laminated wood grain-like polyolefin material and preparation method and application thereof 金发科技股份有限公司 2024-06-21 CN claimed
CN-117965080-B Low-free polyurethane modified anti-penetration UV gloss oil and preparation method thereof 淄博华天橡塑科技有限公司 2024-06-18 CN claimed
CN-118204067-A Lithium adsorbent, preparation method and application 广东邦普循环科技有限公司 2024-06-18 CN claimed
CN-114989389-B High-closed-cell-rate low-density polyurethane vibration isolator and preparation method thereof 山东奥卓新材料有限公司 2024-06-14 CN claimed
CN-118165472-A Master batch with laminated wood grain imitation effect, preparation method and application 金发科技股份有限公司 2024-06-11 CN claimed
CN-118027616-A Waterproof moisture-permeable film and preparation method thereof 科恒高分子(广东)有限公司 2024-05-14 CN claimed
EP-0161503-A1 Bis-phosphonium salts and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-21 EP claimed
EP-0143147-A2 Process for thin layer chromatographic separation of enantiomers Degussa Aktiengesellschaft (DE) 1985-06-05 EP claimed
EP-0044186-B1 PROCESS FOR PRODUCING 5-METHYLFURFURAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-28 EP claimed
EP-0027050-B1 CEPHALOSPORIN DERIVATIVES, THEIR PREPARATION AND THEIR USE ELI LILLY AND COMPANY (US) 1983-10-05 EP claimed
US-4317752-A POLYURETHANE FOAMS; INSULATION; CONSTRUCTION MATERIALS BLOUNT DAVID H 1982-03-02 US claimed
US-4287094-A SILICON SUBSTITUTED DIALKYL OR DIARYL SULFIDES AS LIGANDS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-09-01 US claimed
US-4280006-A Process for the production of polyisocyanate silicate plastics utilizing an alkali metal cellulose silicate condensation product BLOUNT DAVID H 1981-07-21 US claimed
US-4262108-A FIREPROOF CONSTRUCTION MATERIALS, INSULATION BLOUNT DAVID H 1981-04-14 US claimed
US-4153764-A Process for the production of polyisocyanate organic silicate solid/cellular solid product BLOUNT DAVID H 1979-05-08 US claimed
US-3981831-A REACTION OF ORGANIC POLYISOCYANATE WITH ALKALI METAL SILICATE OR SILICA SOL BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US claimed