Ether

Ether

SCHEMBL463356

C1CCOCC1.CCOCC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TSHR P16473 2/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL4417828 1.00 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Ether SCHEMBL1559716 1.00 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL2114570 0.97 ALDH1A1 (0.50) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL3966212 0.97 ALDH1A1 (0.50) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL139042 0.97 ALDH1A1 (0.50) ALDH1A1TSHRHTTLMNAPOLB
Dioxane SCHEMBL8034299 0.94 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL28266595 0.94 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL28163248 0.94 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL8982353 0.94 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB
Tetrahydrofuran SCHEMBL10676279 0.94 ALDH1A1 (0.47) ALDH1A1TSHRHTTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662318-B Iloprost key intermediate and preparation method thereof 上海医药工业研究院 2024-02-02 CN claimed
CN-111662318-A Iloprost key intermediate and preparation method thereof 上海医药工业研究院 2020-09-15 CN claimed
CN-101759601-B Method for preparing chiral alpha-unnatural amino acid by transition metal complex OKEANOS TECH CO LTD 2013-07-24 CN claimed
CN-102617343-A Adsorption chromatography purification method for 8-acetoxy caprylic aldehyde SHIJIAZHUANG VIAO CHEMICAL CO LTD 2012-08-01 CN claimed
US-8124789-B2 Method for producing glycosylated indole compound and antibody against the compound RIKEN (JP) 2012-02-28 US claimed
CN-101759601-A Method for preparing chiral alpha-unnatural amino acid by transition metal complex OKEANOS TECH CO LTD 2010-06-30 CN claimed
US-20100028329-A1 METHOD FOR PRODUCING GLYCOSYLATED INDOLE COMPOUND AND ANTIBODY AGAINST THE COMPOUND RIKEN (JP) 2010-02-04 US claimed
WO-2005058246-A2 METHOD FOR PREPARING RADIOLABELED THYMIDINE MOLECULAR TECHNOLOGIES, INC. (US) 2005-06-30 WO claimed
US-20050131224-A1 Method for preparing radiolabeled thymidine CTI PET SYSTEMS, INC. 2005-06-16 US claimed
EP-0520265-B1 Positive working radiation-sensitive composition with disulfone acid generators BASF AG (DE) 1999-11-17 EP claimed
CN-112351781-B Imidazodiazepine diketones and methods of use thereof 金翅雀生物公司 2024-07-02 CN disclosed
CN-118215506-A Anthracycline derivative linker reagent, antibody-drug conjugate and method 内尔维亚诺医疗科学公司 2024-06-18 CN disclosed
CN-118108576-A Method for removing tetrahydropyran protecting groups on alcohols and phenols 南京工业大学 2024-05-31 CN disclosed
CN-118059093-A Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis 卡斯西部储备大学 2024-05-24 CN disclosed
CN-110799190-B Heterocyclic compounds 卡都瑞恩医药有限公司 2024-04-19 CN disclosed
EP-0038160-A1 Quinone compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1981-10-21 EP disclosed
US-4197286-A ANTI-TESTOSTERONE SERUM FOR USE OF RADIOIMMUNOASSAY METHODS TO MEASURE TESTOSTERONE SOUTHWEST RESEARCH INSTITUTE (US) 1980-04-08 US disclosed
US-4144251-A PROSTAGLANDINS AMERICAN HOME PRODUCTS CORPORATION (US) 1979-03-13 US disclosed
US-4048328-A HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS AMERICAN HOME PRODUCTS CORPORATION (US) 1977-09-13 US disclosed
US-3983154-A Racemic prostaglandins of the 2-series and analogs thereof THE UPJOHN COMPANY (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131224-A1 Method for preparing radiolabeled thymidine TYMP, TYMS, DUT ALDH1A1 2386/4885TSHR 583/4885HTT 2422/4885
US-20100028329-A1 METHOD FOR PRODUCING GLYCOSYLATED INDOLE COMPOUND AND ANTIBODY AGAINST THE COMPOUND TPH1, IDO1, TPH2 ALDH1A1 803/4885TSHR 310/4885HTT 2018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.