Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.64 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13951713 | 0.85 | KCNMA1 (0.58) | STAT3P2RX1TMPRSS4KCNMA1 | |
| SCHEMBL14380922 | 0.82 | STAT3 (0.67) | STAT3GRM5P2RX1TMPRSS4PLAU | |
| SCHEMBL3893328 | 0.82 | STAT3 (0.67) | STAT3GRM5P2RX1TMPRSS4PLAU | |
| SCHEMBL13907159 | 0.82 | STAT3 (0.61) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4755898 | 0.79 | STAT3 (0.63) | STAT3GRM5P2RX1TMPRSS4PLAU | |
| SCHEMBL5797958 | 0.78 | STAT3 (1.00) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2698585 | 0.78 | STAT3 (0.65) | STAT3GRM5P2RX1TMPRSS4PLAU | |
| SCHEMBL29908285 | 0.78 | STAT3 (1.00) | STAT3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13907160 | 0.78 | STAT3 (0.64) | STAT3P2RX1PLAUF2F10 | |
| SCHEMBL13951719 | 0.76 | RAB9A (0.43) | STAT3MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035788-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2009-03-19 | — | — | WO | disclosed |