Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 0.68 |
| ▸ | RAB9A | P51151 | 11/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | PKM | P14618 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MLNR | O43193 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908285 | 1.00 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5795075 | 0.91 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29908284 | 0.91 | STAT3 (1.00) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25063050 | 0.89 | STAT3 (0.80) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25063001 | 0.87 | STAT3 (0.80) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30771758 | 0.86 | STAT3 (0.75) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12974209 | 0.86 | STAT3 (0.75) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12974224 | 0.86 | STAT3 (0.75) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24460217 | 0.83 | STAT3 (0.71) | STAT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5798377 | 0.83 | NPC1 (0.75) | STAT3NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| US-11850237-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2023-12-26 | — | — | US | disclosed |
| CN-116456980-A | Application of thiazole compounds in preparation of medicines for treating and preventing cancers | 北京大学 | 2023-07-18 | — | — | CN | disclosed |
| EP-3895706-A1 | THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS | Romark Laboratories, L.C. (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20210177809-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2021-06-17 | — | — | US | disclosed |
| CN-112957358-A | Application of nitazoxanide and derivatives thereof in preparing medicines for preventing and treating bone destructive diseases | 北京大学第三医院（北京大学第三临床医学院） | 2021-06-15 | — | — | CN | disclosed |
| US-10912768-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190307730-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2019-10-10 | — | — | US | disclosed |
| US-10363243-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2018-03-22 | — | — | US | disclosed |
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2015-09-10 | — | — | US | disclosed |
| US-9023877-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2015-05-05 | — | — | US | disclosed |
| US-9023877-B2 | Compounds and methods for treating influenza | ROMARK LABORATORIES L.C. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. | 2010-12-30 | — | — | US | disclosed |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. | 2010-12-30 | — | — | US | disclosed |
| WO-2010151577-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | ROMARK LABORATORIES L.C. (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20070015803-A1 | Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents | ROMARK LABORATORIES L.C. | 2007-01-18 | — | — | US | disclosed |
| US-20070015803-A1 | Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents | ROMARK LABORATORIES L.C. | 2007-01-18 | — | — | US | disclosed |
| US-20060194853-A1 | Alkyl benzamides | LAMINAR DIRECT CAPITAL, L.L.C. | 2006-08-31 | — | — | US | disclosed |
| WO-2006042195-A1 | ALKYL BENZAMIDES | ROMARK LABORATORIES, L.C. (US) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250768-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20070015803-A1 | Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents | HSP90B1, HSPA5, P4HB | STAT3 3390/4885NPC1 999/4885RAB9A 2688/4885 |
| US-10912768-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20180078533-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20210177809-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20190307730-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20100330173-A1 | COMPOUNDS AND METHODS FOR TREATING INFLUENZA | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-11850237-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
| US-20060194853-A1 | Alkyl benzamides | SAMHD1, PIGS, BTD | STAT3 2811/4885NPC1 669/4885RAB9A 1728/4885 |
| US-10363243-B2 | Compounds and methods for treating influenza | HIF1AN, HAVCR2, NEU1 | STAT3 2441/4885NPC1 473/4885RAB9A 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.