SCHEMBL13908933

SCHEMBL13908933

Nc1ccc(-c2cc3ccccc3s2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 1.00
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA9 Q16790 1/20 0.63
HSD17B1 P14061 1/20 0.56
HSD17B2 P37059 1/20 0.56
ERN1 O75460 2/20 0.50
HDAC2 Q92769 1/20 0.49
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
CYP2A6 P11509 1/20 0.44
ASIC3 Q9UHC3 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.44
MGLL Q99685 1/20 0.44
IKBKB O14920 1/20 0.43
FYN P06241 1/20 0.43
TNK2 Q07912 1/20 0.43
NQO1 P15559 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32677328 0.90 APP (0.81) APPCA1CA2CA9HSD17B1
SCHEMBL27159530 0.90 APP (0.81) APPCA1CA2CA9HSD17B1
SCHEMBL4984272 0.85 APP (0.74) APPCA1CA2CA9HSD17B1
SCHEMBL23555697 0.84 APP (0.72) APPCA1CA2CA9HSD17B1
SCHEMBL5768436 0.84 APP (0.72) APPCA1CA2CA9HSD17B1
SCHEMBL29766071 0.84 APP (0.71) APPCA1CA2CA9HSD17B1
SCHEMBL163523 0.84 APP (0.71) APPCA1CA2CA9HSD17B1
Bromide SCHEMBL31564934 0.82 APP (0.69) APPCA1CA2CA9HSD17B1
SCHEMBL13299941 0.82 APP (0.69) APPCA1CA2CA9ESR1
SCHEMBL27631114 0.82 HSD17B1 (0.77) APPCA1CA2CA9HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029148-A N-phenyl-3- (2, 5-dioxopyrrolidin-1-yl) propionamide derivatives and similar compounds as DUX4 inhibitors for the treatment of, for example, neuromuscular diseases 阿勒泰治疗公司 2026-05-12 CN disclosed
US-20250386668-A1 AMINE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE, ELECTRONIC APPARATUS, AND ELECTRONIC DEVICE INCLUDING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2025-12-18 US disclosed
EP-4553074-A1 AMINE COMPOUND, AND ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTRONIC EQUIPMENT, AND ELECTRONIC ELEMENT CONTAINING SAME Hodogaya Chemical Co., Ltd. (JP) 2025-05-14 EP disclosed
CN-119487025-A Amine compound, and organic electroluminescent element, electronic device and electronic element each containing the same 保土谷化学工业株式会社 2025-02-18 CN disclosed
CN-118043318-A Novel compound for capping layer and organic light-emitting element comprising same 株式会社东进世美肯 2024-05-14 CN disclosed
US-20230255103-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2023-08-10 US disclosed
EP-4177254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2023-05-10 EP disclosed
WO-2021261851-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-12-30 WO disclosed
EP-1539151-B1 BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY GENESOFT PHARMACEUTICALS INC (US) 2009-03-18 EP disclosed
US-7498349-B2 Biaryl compounds having anti-infective activity GENESOFT PHARMACEUTICALS, INC. (US) 2009-03-03 US disclosed
US-20080106190-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed
US-20080106190-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080106190-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, SLC18A2, SLC18A3 APP 547/4885CA1 3673/4885CA2 3086/4885
US-20230255103-A1 ORGANIC ELECTROLUMINESCENT DEVICE EZH1, EPCAM, EED APP 3994/4885CA1 4547/4885CA2 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.