Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947758 | 0.79 | ENPP3 (0.39) | ENPP3ALPLXIAPCYP1A2PARP1 | |
| SCHEMBL4035386 | 0.76 | AHR (0.35) | ENPP3ALPLXIAPCYP1A2PARP1 | |
| SCHEMBL5847269 | 0.76 | ENPP3 (0.33) | ENPP3ALPLXIAPCYP1A2PARP1 | |
| SCHEMBL30521268 | 0.72 | KDM4E (0.38) | ENPP3ALPLXIAPCYP1A2ALDH1A1 | |
| SCHEMBL19857547 | 0.71 | CDK8 (0.43) | ENPP3ALPLXIAPCYP1A2PARP1 | |
| SCHEMBL434570 | 0.63 | MAP4K4 (0.54) | ALDH1A1NPC1RAB9AMAPTPOLB | |
| SCHEMBL14864848 | 0.62 | MAPK8 (0.38) | CYP1A2PARP1ALDH1A1NPC1RAB9A | |
| SCHEMBL16417590 | 0.61 | DYRK1A (0.35) | ENPP3ALPLXIAPCYP1A2ALDH1A1 | |
| SCHEMBL21407548 | 0.60 | KMT2A (0.38) | CYP1A2NPC1HTTMEN1KMT2A | |
| SCHEMBL10231627 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555265-B1 | 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2009-03-25 | — | — | EP | disclosed |