Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.54 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 10/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743642 | 0.76 | RAB9A (0.41) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL10129496 | 0.75 | MAP4K4 (0.47) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL651412 | 0.75 | MAP4K4 (0.47) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL4899669 | 0.75 | CCR1 (0.52) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL7381473 | 0.75 | TP53 (0.62) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL23535657 | 0.74 | NPC1 (0.46) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL14809152 | 0.74 | MAP4K4 (0.46) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL2849283 | 0.74 | MAP4K4 (0.46) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL1269053 | 0.74 | MAP4K4 (0.50) | MAP4K4ABL1MAPK8CSNK1A1CDK7 | |
| SCHEMBL13569111 | 0.74 | MAP4K4 (0.46) | MAP4K4ABL1MAPK8CSNK1A1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | claimed |
| WO-2026106389-A1 | NMT INHIBITOR AND USE THEREOF | 주식회사 이노보테라퓨틱스 | 2026-05-21 | — | — | WO | disclosed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| US-12336537-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-24 | — | — | US | disclosed |
| US-12024510-B2 | Pyrazolopyridine-diamides, their use as insecticide and processes for preparing the same | PI INDUSTRIES LTD. (IN) | 2024-07-02 | — | — | US | disclosed |
| US-12018024-B2 | Compounds and compositions for the treatment of cryptosporidiosis | NOVARTIS AG (CH) | 2024-06-25 | — | — | US | disclosed |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | ASCENEURON SA (CH) | 2024-06-25 | — | — | US | disclosed |
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024097355-A1 | DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS | VICINITAS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024059845-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-21 | — | — | WO | disclosed |
| EP-0191401-B1 | NOVEL ANTIALLERGIC AGENTS AND PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4923871-A | ANTITUMOR | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0270926-A2 | Agents promoting the activity of some antitumor agents and methods for their production | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-06-15 | — | — | EP | disclosed |
| US-4680398-A | Pyrazolo[1,5-a]pyridines and benzimidazoles, useful as antiallergic agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0121197-B1 | PYRAZOLOPYRIDINE DERIVATIVES, THERAPEUTIC COMPOSITIONS COMPRISING SAME, AND PROCESS THEREOF | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1986-11-20 | — | — | EP | disclosed |
| EP-0191401-A2 | Novel antiallergic agents and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4559402-A | ANTICOAGULANTS | KYORIN SEIYAKI KABUSHIKI KAISHA (JP) | 1985-12-17 | — | — | US | disclosed |
| EP-0121197-A1 | Pyrazolopyridine derivatives, therapeutic compositions comprising same, and process thereof | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4097483-A | HYPOTENSIVE AND ANTISPASMODIC AGENT | KYORIN PHARMACEUTICAL CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4028370-A | SMOOTH MUSCLE RELAXANTS, CEREBRAL AND CORONARY DILATORS, HYPOTENSIVE AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JA) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018024-B2 | Compounds and compositions for the treatment of cryptosporidiosis | SLC10A2, SI, SLC10A1 | MAP4K4 2080/4885ABL1 562/4885MAPK8 3091/4885 |
| US-12024510-B2 | Pyrazolopyridine-diamides, their use as insecticide and processes for preparing the same | DDT, QDPR, CYP1A1 | MAP4K4 1130/4885ABL1 727/4885MAPK8 4165/4885 |
| US-12016852-B2 | Pyrrolidine glycosidase inhibitors | PREP, GAA, DNPEP | MAP4K4 3893/4885ABL1 3613/4885MAPK8 4017/4885 |
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | MAP4K4 4353/4885ABL1 4113/4885MAPK8 4177/4885 |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC1 | MAP4K4 3369/4885ABL1 4510/4885MAPK8 3290/4885 |
| US-12336537-B2 | Fungicidal compositions | CYP51A1, CYP4X1, CYP1B1 | MAP4K4 4401/4885ABL1 1254/4885MAPK8 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.