Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.59 |
| ▸ | RECQL | P46063 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669172 | 0.84 | ALOX15 (0.72) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL10070163 | 0.80 | ALOX15 (0.66) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL13912410 | 0.80 | SHBG (0.64) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL12248156 | 0.79 | SHBG (0.49) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL107203 | 0.77 | TDP1 (0.59) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL7935188 | 0.76 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL7940373 | 0.76 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| SCHEMBL7935183 | 0.76 | ALOX15 (0.70) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| Nordihydroguaiaretic Acid SCHEMBL13906133 | 0.75 | ALOX15 (1.00) | ALOX15RECQLKDM4ETDP1ALOX12 | |
| Masoprocol SCHEMBL3818 | 0.75 | ALOX15 (1.00) | ALOX15RECQLKDM4ETDP1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076241-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | NERITES CORPORATION | 2009-03-19 | — | — | US | disclosed |