Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.72 |
| ▸ | RECQL | P46063 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nordihydroguaiaretic Acid SCHEMBL29434237 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Masoprocol SCHEMBL3818 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Masoprocol SCHEMBL29350884 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Masoprocol SCHEMBL29355090 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Nordihydroguaiaretic Acid SCHEMBL135976 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Nordihydroguaiaretic Acid SCHEMBL29434238 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Nordihydroguaiaretic Acid SCHEMBL13906133 | 0.85 | ALOX15 (1.00) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| SCHEMBL13912408 | 0.84 | ALOX15 (0.59) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| SCHEMBL6259718 | 0.83 | ALOX15 (0.68) | ALOX15ALOX12RECQLKDM4ETDP1 | |
| Masoprocol SCHEMBL28156467 | 0.83 | ALOX15 (0.96) | ALOX15ALOX12RECQLKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834575-B2 | Cancer therapy | TRIACT THERAPEUTICS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834575-B2 | Cancer therapy | TRIACT THERAPEUTICS, INC. (US) | 2017-12-05 | — | — | US | disclosed |