Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22858694 | 0.91 | LMNA (0.39) | ALDH1A1KDM4EHPGDPYCR1LMNA | |
| SCHEMBL14927150 | 0.87 | CA12 (0.40) | ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL14303919 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11726630 | 0.78 | — | — | |
| SCHEMBL11687445 | 0.75 | DPP4 (0.46) | ALDH1A1LMNADPP4 | |
| SCHEMBL18746575 | 0.75 | LMNA (0.42) | ALDH1A1LMNA | |
| Allidochlor SCHEMBL4273793 | 0.75 | NPC1 (0.35) | ALDH1A1TDP1 | |
| SCHEMBL7200816 | 0.74 | PYCR1 (0.38) | ALDH1A1KDM4EHPGDPYCR1DPP4 | |
| SCHEMBL5710568 | 0.73 | — | — | |
| SCHEMBL12073330 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | CROCC, JAK3, APOBEC3A | ALDH1A1 2522/4885KDM4E 3319/4885HPGD 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.