Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.53 |
| ▸ | HTR3B | O95264 | 2/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 11/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605537 | 1.00 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL602081 | 0.83 | SMYD3 (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL602018 | 0.78 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9876004 | 0.76 | GSK3B (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13914877 | 0.75 | HTR3A (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL601384 | 0.75 | HTR3A (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL602548 | 0.74 | HRH4 (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7427217 | 0.74 | HRH4 (0.56) | HRH4 | |
| SCHEMBL605257 | 0.71 | MEN1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3369156 | 0.70 | PARP1 (0.74) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504426-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-17 | — | — | US | disclosed |
| US-7504426-B2 | Heterocyclic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-17 | — | — | US | disclosed |