Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.74 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370923 | 0.89 | PARP1 (0.71) | PARP1PARP2 | |
| SCHEMBL6017012 | 0.89 | PARP1 (0.71) | PARP1PARP2 | |
| SCHEMBL6016999 | 0.76 | PARP1 (0.50) | PARP1 | |
| SCHEMBL3369864 | 0.75 | PARP1 (0.80) | PARP1PARP2 | |
| SCHEMBL7422467 | 0.73 | KDM4E (0.54) | PARP1 | |
| SCHEMBL8952887 | 0.72 | KDM4E (0.62) | PARP1 | |
| SCHEMBL3368858 | 0.72 | PARP1 (0.53) | PARP1PARP2 | |
| SCHEMBL311504 | 0.70 | KDM4E (0.56) | PARP1PARP2 | |
| SCHEMBL605537 | 0.70 | HTR3E (0.53) | PARP1 | |
| SCHEMBL13914873 | 0.70 | HTR3E (0.53) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | disclosed |