Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408880 | 0.94 | KDM4E (0.52) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL12727899 | 0.89 | KDM4E (0.52) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL18078699 | 0.89 | SMN1; SMN2 (0.51) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL10160337 | 0.88 | KDM4E (0.55) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL10726997 | 0.85 | FYN (0.58) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL28373020 | 0.82 | CYP2A6 (0.74) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL18419721 | 0.81 | FYN (0.52) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL10964644 | 0.81 | KDM1A (0.47) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL2827765 | 0.81 | FYN (0.56) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 | |
| SCHEMBL12436893 | 0.80 | CDK8 (0.46) | CYP2C9CYP2E1CYP3A4CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090058276-A1 | METAL-CONTAINING POLYMERS and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-03-05 | — | — | US | disclosed |
| US-20090058276-A1 | METAL-CONTAINING POLYMERS and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090058276-A1 | METAL-CONTAINING POLYMERS and uses thereof | PICALM, PUF60, THEM6 | CYP2C9 4272/4885CYP2E1 4633/4885CYP3A4 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.