SCHEMBL1391983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1390599	0.89	ACACB (0.50)	ALDH1A1KMT2AACACBNPC1
	SCHEMBL1390744	0.87	KDM4E (0.43)	ALDH1A1SMN1; SMN2ACACBKDM4ELMNA
	SCHEMBL1391430	0.87	ACACB (0.52)	ALDH1A1ACACBLMNA
	SCHEMBL1391485	0.87	ACACB (0.48)	ALDH1A1ACACB
	SCHEMBL7924591	0.86	TAS1R3 (0.57)	TAS1R3TAS1R1ALDH1A1KMT2AKDM4E
	SCHEMBL1391301	0.84	ACACB (0.54)	ACACB
	SCHEMBL1390698	0.81	CA12 (0.50)	MAOATAS1R3TAS1R1ALDH1A1SMN1; SMN2
	SCHEMBL1390663	0.81	ALOX5 (0.50)	MAOATAS1R3TAS1R1SMN1; SMN2KMT2A
	SCHEMBL1391686	0.80	ACACB (0.43)	MAOASMN1; SMN2ACACB
	SCHEMBL1391226	0.80	NPC1 (0.49)	ALDH1A1SMN1; SMN2KMT2AACACBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.