Methacrylic Acid

Methacrylic Acid

SCHEMBL160887

C=C(C)C(=O)O.C=CC(=O)NCC(CC)S(=O)(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300 0.91 ZDHHC20 (0.44) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acrylic Acid SCHEMBL7528349 0.89 ZDHHC20 (0.41) TSHRALDH1A1MAPK1TDP1ZDHHC20
Hydrochloric Acid SCHEMBL28069295 0.89 ZDHHC20 (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL686653 0.89 ZDHHC20 (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
Ammonia Solution, Strong SCHEMBL139208 0.89 ZDHHC20 (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acrylamide SCHEMBL8157330 0.85 ZDHHC20 (0.40) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL5668122 0.84 ZDHHC20 (0.39) TSHRALDH1A1MAPK1TDP1ZDHHC20
Crotonic Acid SCHEMBL1001175 0.83 ZDHHC20 (0.36) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL3895877 0.82 ZDHHC20 (0.35) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL631536 0.81 THRB (0.35) TSHRZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8734616-B2 Acrylamide-derived cationic copolymers, and uses thereof S.P.C.M. SA (FR) 2014-05-27 US claimed
US-20120132382-A1 ACRYLAMIDE-DERIVED CATIONIC COPOLYMERS, AND USES THEREOF S.P.C.M. SA (FR) 2012-05-31 US claimed
US-20090087400-A1 BREATHABLE POLYURETHANES, BLENDS, AND ARTICLES TAMARESELVY KRISHNAN 2009-04-02 US claimed
EP-1888175-A1 HAIR FIXING COMPOSITION BASED ON BREATHABLE POLYURETHANES Lubrizol Advanced Materials, Inc. (US) 2008-02-20 EP claimed
WO-2006124250-A1 HAIR FIXING COMPOSITION BASED ON BREATHABLE POLYURETHANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2006-11-23 WO claimed
US-20060134049-A1 Hair styling compositions KEENAN ANDREA C 2006-06-22 US claimed
US-20050209428-A1 Breathable polyurethanes, blends, and articles LUBRIZOL ADVANCED MATERIALS, INC. 2005-09-22 US claimed
US-20240158557-A1 MANUFACTURED POLYMERS HAVING ALTERED OLIGOSACCHARIDE OR POLYSACCHARIDE FUNCTIONALITY OR NARROWED OLIGOSACCHARIDE DISTRIBUTION, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND METHODS OF USING THEM NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-05-16 US disclosed
EP-4341317-A1 MANUFACTURED POLYMERS HAVING ALTERED OLIGOSACCHARIDE OR POLYSACCHARIDE FUNCTIONALITY OR NARROWED OLIGOSACCHARIDE DISTRIBUTION, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND METHODS OF USING THEM Nouryon Chemicals International B.V. (NL) 2024-03-27 EP disclosed
CN-117730109-A Artificial polymers with altered oligosaccharide or polysaccharide functionality or narrow oligosaccharide distribution, methods of making the same, compositions comprising the same, and methods of use thereof 诺力昂化学品国际有限公司 2024-03-19 CN disclosed
US-20240065949-A1 ALKALI-SWELLABLE MULTI-FUNCTIONAL RHEOLOGY MODIFIERS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-02-29 US disclosed
US-11833233-B2 Alkali-swellable multi-functional rheology modifiers NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-12-05 US disclosed
WO-2022243533-A1 MANUFACTURED POLYMERS HAVING ALTERED OLIGOSACCHARIDE OR POLYSACCHARIDE FUNCTIONALITY OR NARROWED OLIGOSACCHARIDE DISTRIBUTION, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND METHODS OF USING THEM NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-11-24 WO disclosed
WO-2005092273-A2 METHOD OF COMPATIBILIZING CATIONIC MATERIALS WITH ANIONIC POLYMERS NOVEON IP HOLDINGS CORP. (US) 2005-10-06 WO disclosed
US-20050209428-A1 Breathable polyurethanes, blends, and articles LUBRIZOL ADVANCED MATERIALS, INC. 2005-09-22 US disclosed
US-20040170587-A1 Method of compatibilizing cationic materials with anionic polymers LUBRIZOL ADVANCED MATERIALS, INC. 2004-09-02 US disclosed
US-6753388-B1 WATER-SOLUBLE, CROSSLINKED POLYMERS COMPRISING (CO)MONOMERS OF (METH)ACRYLAMIDE, (METH)ACRYLIC ACID, SODIUM (METH)ACRYLATE, AMMONIUM (METH)ACRYLATE, 2-ACRYLAMIDO-2-METHYLPROPANESULFONIC ACID, AND/OR DIALKYLAMINOALKYL (METH)ACRYLATE OR SALTS NALCO COMPANY 2004-06-22 US disclosed
US-6605674-B1 Structurally-modified polymer flocculants ONDEO NALCO COMPANY 2003-08-12 US disclosed
US-20030143179-A1 Use of xanthan gum as a hair fixative NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2003-07-31 US disclosed
US-20030108505-A1 Use of xanthan gum as a hair fixative AKZO NOBEL N.V. (NL) 2003-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240065949-A1 ALKALI-SWELLABLE MULTI-FUNCTIONAL RHEOLOGY MODIFIERS PUF60, CUTA, SMURF1 TSHR 4052/4885ALDH1A1 3385/4885MAPK1 3285/4885
US-20040170587-A1 Method of compatibilizing cationic materials with anionic polymers PARN, PARG, PICALM TSHR 3945/4885ALDH1A1 4816/4885MAPK1 4527/4885
US-11833233-B2 Alkali-swellable multi-functional rheology modifiers PUF60, CUTA, SMURF1 TSHR 4052/4885ALDH1A1 3385/4885MAPK1 3285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.