Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 5/20 | 0.82 |
| ▸ | DRD1 | P21728 | 7/20 | 0.66 |
| ▸ | DRD3 | P35462 | 7/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.66 |
| ▸ | HTR1A | P08908 | 5/20 | 0.66 |
| ▸ | HTR2A | P28223 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 5/20 | 0.66 |
| ▸ | HRH1 | P35367 | 5/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.66 |
| ▸ | HTR2B | P41595 | 4/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817056 | 0.90 | SETD7 (1.00) | SETD7DRD1DRD3CHRM2CHRM1 | |
| SCHEMBL9167976 | 0.87 | SETD7 (0.86) | SETD7DRD1DRD3CHRM2CHRM1 | |
| SCHEMBL11780074 | 0.87 | CHRM2 (0.69) | SETD7DRD1DRD3CHRM2CHRM1 | |
| SCHEMBL9631147 | 0.86 | SETD7 (1.00) | SETD7DRD1DRD3CHRM2CHRM1 | |
| SCHEMBL10728179 | 0.80 | DRD1 (0.86) | SETD7DRD1DRD3CHRM2CHRM1 | |
| SCHEMBL11600017 | 0.80 | SETD7 (0.71) | SETD7DRD1DRD3CHRM2CHRM1 | |
| Cyproheptadine SCHEMBL29369949 | 0.79 | SETD7 (1.00) | SETD7DRD1DRD3CHRM2CHRM1 | |
| Cyproheptadine SCHEMBL7923153 | 0.79 | SETD7 (1.00) | SETD7DRD1DRD3CHRM2CHRM1 | |
| Cyproheptadine SCHEMBL4021 | 0.79 | SETD7 (1.00) | SETD7DRD1DRD3CHRM2CHRM1 | |
| Danitracen SCHEMBL2734228 | 0.79 | SETD7 (0.67) | SETD7DRD1DRD3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511064-B2 | Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist | BIOFRONTERA BIOSCIENCE GMBH (DE) | 2009-03-31 | — | — | US | disclosed |
| US-20080152640-A1 | Means and Methods For Treating a Disease Which is Associated With an Excess Transport of Hyaluronan Across a Lipid Bilayer | UNIVERSITATSKLINIKUM MUNSTER (DE) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080152640-A1 | Means and Methods For Treating a Disease Which is Associated With an Excess Transport of Hyaluronan Across a Lipid Bilayer | ABCB1, ABCB11, SLC47A2 | SETD7 4231/4885DRD1 3975/4885DRD3 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.