SCHEMBL139241

SCHEMBL139241

CN1CCCN2CCN(C)CCCN(CC1)CC2

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HTT P42858 1/20 0.37
CHKA P35790 3/20 0.35
LMNA P02545 2/20 0.35
NCF1 P14598 2/20 0.33
CA2 P00918 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
CYP1A2 P05177 1/20 0.33
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4311811 1.00 TDP1 (0.38) TDP1KDM4EHTTCHKALMNA
SCHEMBL12354598 1.00 TDP1 (0.38) TDP1KDM4EHTTCHKALMNA
SCHEMBL10179314 0.97 TDP1 (0.37) TDP1KDM4EHTTCHKALMNA
SCHEMBL5675656 0.97 TDP1 (0.37) TDP1KDM4EHTTCHKALMNA
SCHEMBL17787332 0.97 TDP1 (0.35) TDP1KDM4EHTTCHKALMNA
Hydrochloric Acid SCHEMBL3998282 0.94 TDP1 (0.35) TDP1KDM4EHTTCHKALMNA
Hydrochloric Acid SCHEMBL3998279 0.94 HTT (0.39) TDP1KDM4EHTTCHKALMNA
SCHEMBL4318497 0.89 CHKA (0.35) TDP1KDM4EHTTCHKALMNA
SCHEMBL29875104 0.87 KDM4E (0.32) TDP1KDM4EHTTCHKALMNA
SCHEMBL29874801 0.87 KDM4E (0.32) TDP1KDM4EHTTCHKALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 538 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2661473-B1 ANTISKINNING COMPOSITIONS OMG UK TECH LIMITED (GB) 2021-09-15 EP claimed
EP-3307940-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP claimed
EP-3307941-B1 OXIDATIVE METHOD CATEXEL TECH LIMITED (GB) 2021-03-24 EP claimed
US-10882745-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2021-01-05 US claimed
US-10815616-B2 Oxidative method CATEXEL TECHNOLOGIES LIMITED (GB) 2020-10-27 US claimed
US-20180186634-A1 OXIDATIVE METHOD CATEXEL B.V. (NL) 2018-07-05 US claimed
EP-3307940-A1 OXIDATIVE METHOD Catexel Technologies Limited (GB) 2018-04-18 EP claimed
EP-3307941-A1 OXIDATIVE METHOD Catexel Technologies Limited (GB) 2018-04-18 EP claimed
US-20180094384-A1 OXIDATIVE METHOD CATEXEL B.V. (NL) 2018-04-05 US claimed
EP-3024898-B1 ENCAPSULATED CATALYSTS OMG UK TECH LTD (GB) 2017-11-08 EP claimed
EP-1631653-B1 LIQUID BLEACHING COMPOSITION UNILEVER PLC (GB) 2007-04-04 EP claimed
US-20070004613-A1 Liquid bleaching composition CONOPCO, INC., D/B/A UNILEVER 2007-01-04 US claimed
EP-1157088-B1 STABILIZED BLEACH COMPOSITIONS PROCTER & GAMBLE (US) 2006-01-11 EP claimed
EP-1129095-B1 PROCESS FOR PREPARING CROSS-BRIDGED TETRAAZA MACROCYCLES PROCTER & GAMBLE (US) 2004-09-15 EP claimed
US-6720299-B2 BLEACH WITH POLYMER COATING UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-04-13 US claimed
US-6555681-B1 Reducing and cleaving an diammonium salt of a tetraaza-tetracyclic compound using a stoichiometric amount of an alkali boron hydride at a pH of 11 to a tetraaza-bicyclic compound; transition metal complexes as bleach catalysts PROCTER & GAMBLE COMPANY 2003-04-29 US claimed
US-20020173440-A1 Bleaching composition of enhanced stability and a process for making such a composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-11-21 US claimed
EP-1129164-A1 BLEACH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-09-05 EP claimed
WO-2000029537-A1 BLEACH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-05-25 WO claimed
WO-1999005084-A1 PROCESS FOR MAKING ALKYLBENZENESULFONATE SURFACTANTS FROM ALCOHOLS AND PRODUCTS THEREOF THE PROCTER & GAMBLE COMPANY (US) 1999-02-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815616-B2 Oxidative method CAT, LPO, MPO TDP1 2935/4885KDM4E 3828/4885HTT 2048/4885
US-10882745-B2 Oxidative method CAT, LPO, GPX4 TDP1 4126/4885KDM4E 3796/4885HTT 1375/4885
US-20180094384-A1 OXIDATIVE METHOD CAT, LPO, MPO TDP1 2935/4885KDM4E 3828/4885HTT 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.