Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441754 | 0.83 | CYP2C19 (0.63) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL7863949 | 0.82 | KMT2A (0.48) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL12233194 | 0.82 | KMT2A (0.48) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL18389980 | 0.81 | HRH3 (0.50) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL7862569 | 0.81 | KMT2A (0.47) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL18389973 | 0.80 | KDM4E (0.65) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL3531319 | 0.78 | KMT2A (0.48) | KMT2ACYP2C19KDM4ECYP2D6POLB | |
| SCHEMBL13754285 | 0.78 | HTT (0.65) | KMT2AHTT | |
| SCHEMBL22753493 | 0.77 | CHRNB2 (0.50) | KMT2APOLBGLATSHRNAMPT | |
| SCHEMBL674660 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | KMT2A 3083/4885CYP2C19 100/4885KDM4E 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.