Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926108 | 0.90 | MAPT (0.37) | KDM4ESMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL13926705 | 0.89 | MAPT (0.39) | KDM4EHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL13926102 | 0.83 | KMT2A (0.40) | KDM4ESMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL13294092 | 0.74 | NPY1R (0.32) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL13294088 | 0.73 | RORC (0.32) | — | |
| SCHEMBL13926076 | 0.70 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTMEN1KMT2ATDP1 | |
| SCHEMBL13926696 | 0.69 | MEN1 (0.36) | KDM4EMAPTMEN1KMT2AGAA | |
| SCHEMBL3933371 | 0.68 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL13926446 | 0.67 | KMT2A (0.67) | SMN1; SMN2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL13908688 | 0.63 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037325-A2 | THIOL/DISULFIDE INDOLE-DERIVED, STYRYL DYE, DYE COMPOSITION COMPRISING SAID DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |