Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926079 | 0.83 | KDM4E (0.37) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL13294092 | 0.76 | NPY1R (0.32) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13926705 | 0.75 | MAPT (0.39) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL13294088 | 0.73 | RORC (0.32) | — | |
| SCHEMBL13926108 | 0.73 | MAPT (0.37) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL23046854 | 0.66 | KMT2A (0.69) | KMT2AMAPTMEN1NPC1CASP3 | |
| SCHEMBL4530484 | 0.64 | MEN1 (0.49) | KMT2AMAPTMEN1NPC1CASP3 | |
| SCHEMBL4530482 | 0.64 | MEN1 (0.49) | KMT2AMAPTMEN1NPC1CASP3 | |
| SCHEMBL8494191 | 0.63 | KMT2A (0.73) | KMT2AMAPTMEN1NPC1CASP3 | |
| SCHEMBL8494188 | 0.63 | KMT2A (0.73) | KMT2AMAPTMEN1NPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037325-A2 | THIOL/DISULFIDE INDOLE-DERIVED, STYRYL DYE, DYE COMPOSITION COMPRISING SAID DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |