Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926079 | 0.89 | KDM4E (0.37) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL13926108 | 0.80 | MAPT (0.37) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL13926102 | 0.75 | KMT2A (0.40) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL13294092 | 0.70 | NPY1R (0.32) | KDM4EMAPK1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL13294088 | 0.68 | RORC (0.32) | — | |
| SCHEMBL18271504 | 0.66 | KDM4E (0.56) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL7601817 | 0.65 | MEN1 (0.64) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL12721222 | 0.63 | FBP1 (0.48) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL5239507 | 0.59 | ALDH1A1 (0.63) | MAPTKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL3933371 | 0.59 | SMN1; SMN2 (0.71) | MAPTKMT2AMEN1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037325-A2 | THIOL/DISULFIDE INDOLE-DERIVED, STYRYL DYE, DYE COMPOSITION COMPRISING SAID DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |