Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GRK2 | P25098 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543475 | 0.81 | PLCG1 (0.55) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21431073 | 0.81 | PLCG1 (0.61) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5387555 | 0.80 | PLCG1 (0.59) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3927298 | 0.80 | KEAP1 (0.54) | ALDH1A1CYP3A4CYP2C9CYP2C19CA2 | |
| SCHEMBL14379397 | 0.79 | PLCG1 (0.59) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26201360 | 0.78 | MMP8 (0.61) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5446197 | 0.78 | PLCG1 (0.57) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3576166 | 0.78 | PLCG1 (0.57) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5104880 | 0.78 | PLCG1 (0.57) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1941210 | 0.78 | CA2 (0.67) | PLCG1ALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498415-B2 | Recombinant antibody against human insulin-like growth factor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |