Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 12/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928759 | 0.90 | FFAR2 (0.42) | CCR5KMT2AMEN1FFAR2 | |
| SCHEMBL13928763 | 0.83 | HPGD (0.46) | KMT2AMEN1SLC6A2 | |
| SCHEMBL13928749 | 0.82 | CCR5 (0.43) | CCR5KMT2AMEN1 | |
| SCHEMBL4202747 | 0.82 | ALDH1A1 (0.42) | KMT2AMEN1 | |
| SCHEMBL4214656 | 0.81 | CCR5 (0.38) | CCR5KDM5A | |
| SCHEMBL13928734 | 0.79 | POLB (0.46) | CCR5KMT2AMEN1 | |
| SCHEMBL13928743 | 0.78 | FFAR2 (0.39) | CCR5FFAR2 | |
| SCHEMBL13928746 | 0.77 | CCR5 (0.38) | CCR5 | |
| SCHEMBL4207234 | 0.77 | SLC6A4 (0.39) | KMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL13928756 | 0.75 | CCR5 (0.37) | CCR5SLC6A2SLC6A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |