SCHEMBL139327

SCHEMBL139327

COC(=O)c1ccc(C(=O)Oc2ccc(C3(c4ccc(OC)cc4C)CCCCC3)c(C)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ KMT2A Q03164 5/20 0.45
▸ CYP3A4 P08684 4/20 0.42
▸ GBA1 P04062 1/20 0.42
▸ HGFAC Q04756 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ NPC1 O15118 2/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ PDE7A Q13946 1/20 0.40
▸ ACR P10323 3/20 0.40
▸ CYP26A1 O43174 2/20 0.39
▸ PRSS1 P07477 2/20 0.39
▸ POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14007592 0.87 KMT2A (0.47) KMT2ACYP3A4GBA1LMNASMN1; SMN2
SCHEMBL141564 0.84 KMT2A (0.48) KMT2ACYP3A4SMN1; SMN2KDM4EMEN1
SCHEMBL14700574 0.84 ACHE (0.41) CA2KMT2ALMNASMN1; SMN2KDM4E
SCHEMBL14802305 0.81 PDE7A (0.40) KMT2ASMN1; SMN2PDE7APOLB
SCHEMBL139339 0.79 CA1 (0.57) CA1CA2KMT2AHGFACLMNA
SCHEMBL13864906 0.75 TDP1 (0.53) CA1CA2KMT2AGBA1HGFAC
SCHEMBL12345950 0.75 OPRM1 (0.38) KMT2ACYP3A4LMNASMN1; SMN2KDM4E
SCHEMBL14727677 0.74 KMT2A (0.41) KMT2ASMN1; SMN2MEN1CYP26A1RAB9A
SCHEMBL16775320 0.73 SLC6A2 (0.51) CA1CA2KMT2AGBA1LMNA
SCHEMBL12578509 0.72 TDP1 (0.45) CA1CA2KMT2ACYP3A4GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
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