Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748497 | 1.00 | KLK5 (0.64) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL8283132 | 1.00 | KLK5 (0.64) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL27486450 | 0.90 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL27796636 | 0.90 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL8486327 | 0.90 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL27502332 | 0.90 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL6896461 | 0.89 | ATM (0.61) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL9848360 | 0.88 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL8534875 | 0.88 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL | |
| SCHEMBL6444857 | 0.88 | KLK5 (0.63) | KLK5ATMCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662164-B2 | Non-beta lactam antibiotics | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190127340-A1 | NON-BETA LACTAM ANTIBIOTICS | UNIVERSITY OF NOTRE DAME DU LAC | 2019-05-02 | — | — | US | disclosed |
| US-20090048227-A1 | Substituted-1-Phthalazinamines As Vr- 1 Antagonists | MERCK SHARP & DOHME CORP. | 2009-02-19 | — | — | US | disclosed |
| US-20090048227-A1 | Substituted-1-Phthalazinamines As Vr- 1 Antagonists | MERCK SHARP & DOHME CORP. | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048227-A1 | Substituted-1-Phthalazinamines As Vr- 1 Antagonists | TRPV1, TRPV2, TRPV5 | KLK5 1102/4885ATM 4685/4885CTSS 2542/4885 |
| US-10662164-B2 | Non-beta lactam antibiotics | OXA1L, O60361, CUTA | KLK5 3015/4885ATM 3606/4885CTSS 3480/4885 |
| US-20190127340-A1 | NON-BETA LACTAM ANTIBIOTICS | OXA1L, O60361, CUTA | KLK5 3015/4885ATM 3606/4885CTSS 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.