Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 4/20 | 0.33 |
| ▸ | RXRG | P48443 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933337 | 1.00 | POLB (0.42) | POLBCYP2C19GRIA2CES1KDM4E | |
| SCHEMBL22823989 | 0.81 | CYP1A2 (0.36) | POLBCYP2C19CES1KDM4ERXRA | |
| SCHEMBL22288462 | 0.77 | PPARG (0.38) | — | |
| SCHEMBL8403545 | 0.76 | POLB (0.61) | POLBCES1HPGD | |
| SCHEMBL707762 | 0.76 | NR1H2 (0.37) | — | |
| SCHEMBL21101910 | 0.76 | POLB (0.46) | POLBCYP2C19GRIA2CES1KDM4E | |
| SCHEMBL13933530 | 0.75 | ALDH1A1 (0.61) | POLBHDAC4L3MBTL1HDAC6HDAC1 | |
| SCHEMBL4071160 | 0.75 | ALDH1A1 (0.61) | POLBHDAC4L3MBTL1HDAC6HDAC1 | |
| SCHEMBL265118 | 0.73 | PIK3CA (0.53) | POLBCES1RXRARXRBRXRG | |
| SCHEMBL22288627 | 0.72 | HPGD (0.55) | RXRARXRBRXRGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090035215-A1 | RADIOFLUORINATION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090035215-A1 | RADIOFLUORINATION | AFF2, AFF1, NUTF2 | POLB 2590/4885CYP2C19 1427/4885GRIA2 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.