Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775630 | 0.92 | POLB (0.55) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL4455 | 0.89 | CA2 (0.62) | POLBCA2CAMK2AALDH1A1LMNA | |
| SCHEMBL8277240 | 0.89 | CA2 (0.62) | POLBCA2KMT2ACAMK2AAKR1B1 | |
| SCHEMBL9149413 | 0.89 | POLB (0.53) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL5536012 | 0.89 | POLB (0.53) | POLBCA2KMT2ACAMK2ACES2 | |
| SCHEMBL564730 | 0.89 | ALDH1A1 (0.54) | POLBCA2KMT2AALDH1A1HPGD | |
| SCHEMBL81559 | 0.89 | CTBP2 (0.53) | POLBKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL14495580 | 0.87 | POLB (0.52) | POLBCA2KMT2ACAMK2ACES2 | |
| SCHEMBL7151365 | 0.87 | KMT2A (0.67) | POLBKMT2AALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL2583907 | 0.87 | CA2 (0.60) | POLBCA2CAMK2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357512-A1 | RESIN COMPOSITION, MOLDED BODY, AND METHOD OF IMPROVING PROPERTY OF RESIN COMPOSITION | IDEMITSU KOSAN CO.,LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
| US-11697708-B2 | Polycarbonate-polyorganosiloxane copolymer, polycarbonate resin composition including same, and molded product thereof | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-11 | — | — | US | disclosed |
| US-11655326-B2 | Molded body containing polycarbonate-polyorganosiloxane copolymer | IDEMITSU KOSAN CO., LTD. (JP) | 2023-05-23 | — | — | US | disclosed |
| US-20230151035-A1 | Preparation method for and application of chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand and iridium catalyst thereof | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2023-05-18 | — | — | US | disclosed |
| US-20230151035-A1 | Preparation method for and application of chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand and iridium catalyst thereof | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2023-05-18 | — | — | US | disclosed |
| EP-4089097-A1 | PREPARATION METHOD FOR AND APPLICATION OF CHIRAL SPIROCYCLIC PHOSPHINE-NITROGEN-PHOSPHINE TRIDENTATE LIGAND AND IRIDIUM CATALYST THEREOF | Zhejiang Jiuzhou Pharmaceutical Co., Ltd (CN) | 2022-11-16 | — | — | EP | disclosed |
| US-11495744-B2 | Organic semiconductor composition, organic thin film, and organic thin film transistor | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2022-11-08 | — | — | US | disclosed |
| CN-108109963-B | Display unit, method of manufacturing the same, and electronic apparatus | 索尼公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20110242191-A1 | INK COMPOSITION, INKJET RECORDING METHOD AND PROCESS FOR PRODUCING MOLDED PRINTED MATERIAL | FUJIFILM CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| WO-2007071396-A2 | PYRAZINOYLGUANIDINE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY OR ALLERGIC CONDITIONS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |
| EP-0196849-A2 | Aminohydroxyalkylbenzene anti-obesity and/or anti-hyperglycaemic agents | BEECHAM GROUP PLC (GB) | 1986-10-08 | — | — | EP | disclosed |
| US-4555537-A | IMIDAZOLINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | POLB 503/4885CA2 1962/4885KMT2A 3176/4885 |
| US-20080312217-A1 | Organic Compounds | TRPA1, TRPV1, CHRM1 | POLB 3189/4885CA2 148/4885KMT2A 3363/4885 |
| US-20230151035-A1 | Preparation method for and application of chiral spirocyclic phosphine-nitrogen-phosphine tridentate ligand and iridium catalyst thereof | SPR, PKD1, ROR1 | POLB 3124/4885CA2 1844/4885KMT2A 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.