Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Miconazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 12/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 5/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 5/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 4/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 4/20 | 1.00 |
| ▸ | CYP17A1 | P05093 | 4/20 | 1.00 |
| ▸ | PGR | P06401 | 4/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 4/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 4/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 4/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 4/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Miconazole SCHEMBL2866 | 1.00 | IDO1 (1.00) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| (R)-Miconazole SCHEMBL2867 | 1.00 | IDO1 (1.00) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| Miconazole SCHEMBL64342 | 1.00 | IDO1 (1.00) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| Miconazole SCHEMBL7647866 | 1.00 | IDO1 (1.00) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| Miconazole SCHEMBL9662051 | 1.00 | IDO1 (1.00) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| (R)-Miconazole SCHEMBL30594078 | 1.00 | IDO1 (1.00) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| Miconazole SCHEMBL9479808 | 0.99 | IDO1 (0.98) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| Miconazole SCHEMBL9479815 | 0.99 | IDO1 (0.98) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| (R)-Miconazole SCHEMBL3367 | 0.99 | IDO1 (0.98) | IDO1CYP2C9CYP3A4LMNACYP1A2 | |
| Miconazole SCHEMBL10575722 | 0.99 | IDO1 (0.98) | IDO1CYP2C9CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 592 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-3222270-B1 | COMPOSITIONS FOR MUCOSAL ADHESION AND USES THEREOF | BIONANOPLUS S L (ES) | 2026-04-29 | — | — | EP | claimed |
| EP-3876949-B1 | DERMAL SKIN PROTECTANT AND CARRIER | INSPIRED MAT STRATEGIES LLC (US) | 2025-08-20 | — | — | EP | claimed |
| EP-3946279-B1 | STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES | SISAF LTD (GB) | 2025-07-23 | — | — | EP | claimed |
| EP-4101437-B1 | BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | SHENZHEN EULIKAN BIOTECHNOLOGY CO LTD (CN) | 2025-06-11 | — | — | EP | claimed |
| EP-4149426-B1 | MUCOADHESIVE TABLET FOR THE TREATMENT OF OROPHARYNGEAL FUNGAL INFECTIONS | VECTANS PHARMA (FR) | 2025-05-28 | — | — | EP | claimed |
| CN-111526873-B | For modulating microbial colonization substituted diphenylacetylenes of (2) | 生物曼迪克斯有限责任公司 | 2025-03-04 | — | — | CN | claimed |
| US-20240390364-A1 | Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions | REID CHRISTOPHER BRIAN (US) | 2024-11-28 | — | — | US | claimed |
| EP-4069690-B1 | POLYMORPHS OF TRIAZOLE ANTIFUNGAL COMPOUND PC945 | PULMOCIDE LTD (GB) | 2024-11-13 | — | — | EP | claimed |
| US-20240245871-A1 | PORTABLE MEDICAL TREATMENT SYSTEM AND METHOD OF USE | VAPOROX, INC. | 2024-07-25 | — | — | US | claimed |
| US-20100144626-A1 | Treatment of Multi-Drug Resistant Bacterial Infections | E-THERAPEUTICS PLC (GB) | 2010-06-10 | — | — | US | claimed |
| CN-1985883-B | Antifungal medicine composition and its preparing method and use | JIANGSU ZEUKOV PHARMACEUTICAL S & T INC | 2010-05-12 | — | — | CN | claimed |
| CN-100429306-C | Tissue culture medium and fast propagation method for Sorbone lily | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2008-10-29 | — | — | CN | claimed |
| US-20070196412-A1 | Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-23 | — | — | US | claimed |
| CN-1985883-A | Antifungal medicine composition and its preparing method and use | ZHONGKANG MEDICINE SCI TECH CO (CN) | 2007-06-27 | — | — | CN | claimed |
| CN-1322862-C | Effervescence tablet of miconazole nitrate for vagina and preparation technique | FUSHOUTAN PHARMACEUTICAL CO LT (CN) | 2007-06-27 | — | — | CN | claimed |
| CN-1314398-C | Cream for treating skin diseases and preparation method thereof | KANG DECHENG (CN) | 2007-05-09 | — | — | CN | claimed |
| CN-1254278-C | Medical ointment, film and tincture | WU TIANXIANG (CN) | 2006-05-03 | — | — | CN | claimed |
| CN-1726910-A | Effervescence tablet of miconazole nitrate for vagina and preparation technique | FUSHOUTAN PHARMACEUTICAL CO LT (CN) | 2006-02-01 | — | — | CN | claimed |
| US-4500540-A | DIETETICS | HOFFMANN-LA ROCHE INC. (US) | 1985-02-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196412-A1 | Composition for the impregnation of fibers, fabrics and nettings imparting a protective activity against pests | GAP43, GRN, DDT | IDO1 2370/4885CYP2C9 1320/4885CYP3A4 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.