Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794601 | 0.91 | L3MBTL1 (0.53) | PTGESMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL4086718 | 0.87 | MAPT (0.51) | PTGESMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL24305898 | 0.86 | SMPD1 (0.56) | PTGESMEN1KMT2AGAARAB9A | |
| SCHEMBL24306566 | 0.84 | L3MBTL1 (0.50) | MEN1KMT2AGAAL3MBTL1MAPT | |
| SCHEMBL21596050 | 0.83 | MAPT (0.59) | MEN1KMT2AGAAL3MBTL1MAPT | |
| SCHEMBL6648626 | 0.83 | PRSS1 (0.49) | PTGESMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL21595981 | 0.82 | MAPT (0.50) | MEN1KMT2AL3MBTL1MAPTHPGD | |
| SCHEMBL19612285 | 0.81 | MAPT (0.53) | PTGESL3MBTL1MAPTHPGDALDH1A1 | |
| SCHEMBL5477791 | 0.81 | ALDH1A1 (0.68) | KMT2AGAAL3MBTL1MAPTHPGD | |
| SCHEMBL17546739 | 0.81 | ALDH1A1 (0.57) | MEN1KMT2AGAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029982-A1 | PROTEIN KINASE INHIBITORS | SUPERGEN, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| US-20080207632-A1 | PROTEIN KINASE INHIBITORS | SUPERGEN, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207632-A1 | PROTEIN KINASE INHIBITORS | ERBB3, ERBB2, AXL | PTGES 4340/4885MEN1 1002/4885KMT2A 624/4885 |
| US-20090029982-A1 | PROTEIN KINASE INHIBITORS | CDK2, PACSIN2, AKT1 | PTGES 2258/4885MEN1 1439/4885KMT2A 736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.