Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261159 | 0.86 | MAOA (0.44) | KMT2ASMN1; SMN2NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11434377 | 0.83 | MAOA (0.46) | KMT2ASMN1; SMN2IDO1MAPTALDH1A1 | |
| SCHEMBL7262688 | 0.77 | KMT2A (0.42) | KMT2AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL10438960 | 0.74 | KMT2A (0.48) | KMT2AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL1649346 | 0.74 | MAOA (0.56) | KMT2AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL10438961 | 0.74 | KMT2A (0.48) | KMT2AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL24143154 | 0.72 | KMT2A (0.42) | KMT2AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL20014974 | 0.72 | POLB (0.50) | KMT2AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL31019490 | 0.72 | KMT2A (0.63) | KMT2ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL2461097 | 0.72 | KMT2A (0.63) | KMT2ASMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009025793-A2 | HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF | SENOMYX, INC. (US) | 2009-02-26 | — | — | WO | disclosed |