Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461097 | 1.00 | KMT2A (0.63) | KMT2ANPC1RAB9APKMALOX15 | |
| Hydrochloric Acid SCHEMBL3748099 | 0.98 | KMT2A (0.61) | KMT2ANPC1RAB9APKMALOX15 | |
| SCHEMBL11407629 | 0.79 | BCAT2 (0.50) | KMT2ANPC1RAB9APKMRNASEH1 | |
| SCHEMBL31019547 | 0.79 | BCAT2 (0.50) | KMT2ANPC1RAB9APKMRNASEH1 | |
| Hydrochloric Acid SCHEMBL11413530 | 0.78 | BCAT2 (0.49) | KMT2ANPC1RAB9ARNASEH1ALDH1A1 | |
| Diftalone SCHEMBL29644941 | 0.77 | KMT2A (1.00) | KMT2ANPC1RAB9APKMALOX15 | |
| Diftalone SCHEMBL35351 | 0.77 | KMT2A (1.00) | KMT2ANPC1RAB9APKMALOX15 | |
| SCHEMBL9225134 | 0.76 | CYP2A6 (0.55) | KMT2ANPC1RAB9ARNASEH1ALDH1A1 | |
| SCHEMBL24143154 | 0.74 | KMT2A (0.42) | KMT2ANPC1RAB9APKMALOX15 | |
| SCHEMBL3169575 | 0.74 | KMT2A (0.63) | KMT2ANPC1RAB9APKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024229228-A3 | 1-OXOISOINDOLIN-2-YL AMIDE ACTIVATORS OF VCP AND DERIVATIVES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2024229228-A2 | 1-OXOISOINDOLIN-2-YL AMIDE ACTIVATORS OF VCP AND DERIVATIVES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024229228-A2 | 1-OXOISOINDOLIN-2-YL AMIDE ACTIVATORS OF VCP AND DERIVATIVES THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024226892-A1 | HYDRAZONE 3H-IMIDAZO(4,5-B)PYRIDINE COMPOUNDS AND USES THEREOF | Verge Analytics, Inc. (US) | 2024-10-31 | — | — | WO | disclosed |
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. | 2024-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254118-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT9 | KMT2A 59/4885NPC1 3757/4885RAB9A 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.