Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24143154 | 0.74 | KMT2A (0.42) | POLBLMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL31019490 | 0.74 | KMT2A (0.63) | SMN1; SMN2MAPTRAB9AKDM4EKMT2A | |
| SCHEMBL8018700 | 0.74 | LMNA (0.50) | POLBLMNASMN1; SMN2CYP2D6MAPT | |
| SCHEMBL7262688 | 0.74 | KMT2A (0.42) | POLBLMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL2461097 | 0.74 | KMT2A (0.63) | SMN1; SMN2MAPTRAB9AKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL3748099 | 0.72 | KMT2A (0.61) | SMN1; SMN2MAPTRAB9AKDM4EKMT2A | |
| SCHEMBL13939593 | 0.72 | KMT2A (0.48) | POLBLMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL21494570 | 0.71 | LMNA (0.47) | POLBLMNASMN1; SMN2CYP2D6MAPT | |
| SCHEMBL21129985 | 0.69 | KMT2A (0.38) | POLBLMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL24886036 | 0.69 | HPGD (0.49) | POLBLMNASMN1; SMN2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018056453-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | 中外製薬株式会社 | 2018-03-29 | — | — | WO | disclosed |