Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020226 | 0.80 | LRRK2 (0.46) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL17978571 | 0.72 | GABRA2 (0.46) | NOTUMRXRAGRIN1GRIN2B | |
| SCHEMBL14320344 | 0.68 | TDO2 (0.49) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL20409480 | 0.67 | NOTUM (0.45) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL22637403 | 0.67 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL2627212 | 0.66 | MAPT (0.50) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL512436 | 0.65 | MAPT (0.39) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL29878633 | 0.65 | MAPT (0.39) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL2658961 | 0.64 | CYP1A2 (0.54) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL1353678 | 0.64 | MAPT (0.46) | ALDH1A1LMNAMAPTMAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473699-B2 | 3-cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents | ASTRAZENECA AB (SE) | 2009-01-06 | — | — | US | disclosed |