SCHEMBL139418

SCHEMBL139418

CCO[Si](CCC(C)C#N)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3344095 0.82 TSHR (0.40) TSHR
SCHEMBL1224950 0.80 TSHR (0.39) TSHR
SCHEMBL574684 0.78 TSHR (0.44) TSHR
SCHEMBL1804121 0.78 TSHR (0.34) TSHR
SCHEMBL27890802 0.78
SCHEMBL444986 0.75
SCHEMBL31548667 0.75
SCHEMBL31734297 0.75
SCHEMBL638552 0.73 OPRM1 (0.39)
SCHEMBL2329614 0.71 TSHR (0.46) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262576-B1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORP (US) 2025-03-12 EP claimed
US-11426707-B2 Composite materials containing nanoparticles and their use in chromatography WATERS TECHNOLOGIES CORPORATION (US) 2022-08-30 US claimed
EP-3189107-B1 HARDCOAT AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2018-11-28 EP claimed
US-20170233591-A1 HARDCOAT AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-08-17 US claimed
EP-3189107-A1 HARDCOAT AND METHOD OF MAKING THE SAME 3M Innovative Properties Company (US) 2017-07-12 EP claimed
CN-106795382-A Hard conating and preparation method thereof 3M创新有限公司 2017-05-31 CN claimed
US-20160263555-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION 2016-09-15 US claimed
WO-2016036507-A1 HARDCOAT AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-10 WO claimed
US-9248383-B2 Composite materials containing nanoparticles and their use in chromatography WATERS TECHNOLOGIES CORPORATION (US) 2016-02-02 US claimed
US-20110049056-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2011-03-03 US claimed
EP-2262576-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY Waters Technologies Corporation (US) 2010-12-22 EP claimed
WO-2009126207-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2009-10-15 WO claimed
US-12623205-B2 Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution WATERS TECHNOLOGIES CORPORATION (US) 2026-05-12 US disclosed
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography WATERS TECHNOLOGIES CORPORATION (US) 2026-04-28 US disclosed
EP-3834927-B1 METHOD FOR PREPARING A SUPERFICIALLY POROUS MATERIAL WATERS TECHNOLOGIES CORP (US) 2026-03-25 EP disclosed
US-20250387778-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2025-12-25 US disclosed
WO-2009126207-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2009-10-15 WO disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
WO-2008103423-A1 POROUS INORGANIC/ORGANIC HYBRID PARTICLES HAVING HIGH ORGANIC CONTENT AND ENHANCED PORE GEOMETRY FOR CHROMATOGRAPHIC SEPARATIONS WATERS INVESTMENTS LIMITED (US) 2008-08-28 WO disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography F11, F12, F2 TSHR 1076/4885
US-12623205-B2 Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution ZYX, FGB, F11 TSHR 3099/4885
US-20250387778-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS C1S, C9, C1R TSHR 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.