Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD4 | P21917 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 5/20 | 0.37 |
| ▸ | DRD1 | P21728 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875974 | 0.84 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDGAAALOX12 | |
| SCHEMBL18471325 | 0.77 | HTR2A (0.39) | KDM4EALDH1A1HPGDHTR2AADRA2A | |
| SCHEMBL13875992 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDCHRNB4CHRNA3 | |
| SCHEMBL20276739 | 0.72 | KMT2A (0.39) | KDM4EALDH1A1HPGDHTR2AADRA2A | |
| SCHEMBL13969348 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1HPGDGAAALOX12 | |
| SCHEMBL20277045 | 0.70 | KMT2A (0.40) | KDM4EALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL13875987 | 0.70 | ALDH1A1 (0.38) | ALDH1A1HPGDALOX12CHRNB4CHRNA3 | |
| SCHEMBL13875985 | 0.68 | HPGD (0.36) | ALDH1A1HPGDGAAHTR2AHTR2C | |
| SCHEMBL17951855 | 0.68 | HPGD (0.48) | HPGDHTR2AADRA2ADRD2DRD4 | |
| SCHEMBL29351597 | 0.67 | MAOA (0.52) | KDM4EALDH1A1HPGDHTR2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410280-B2 | Process for preparing transition metal-carbene complexes | BASF SE (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20090018330-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | BASF SE (DE) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018330-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | AP1M1, C1S, GPS1 | KDM4E 4586/4885ALDH1A1 2893/4885HPGD 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.